Series A(+) – IndieBio – #1 in Early Stage Biotech https://indiebio.co #1 in Early Stage Biotech Tue, 29 Apr 2025 09:35:21 +0000 en-US hourly 1 https://wordpress.org/?v=6.7.2 https://indiebio.co/wp-content/uploads/2025/04/cropped-cropped-indie-bio-logo-512-32x32.png Series A(+) – IndieBio – #1 in Early Stage Biotech https://indiebio.co 32 32 Indee Labs https://indiebio.co/company/indee-labs/ Fri, 11 Apr 2025 22:09:16 +0000 http://localhost:10023/company/indee-labs/ With their microvortex shedding technology, Indee Labs’ cell engineering platform preserves cell function while boasting high recovery efficiencies and each 5 x 10mm chip can process >50 million cells at >2-4 million cells per second and as low as 100uL in processing volume.

This matters to the population of patients who today cannot afford cell therapy due to the high cost associated with their production. With this system, the ability to engineer T-cells rapidly and more efficiently will make cell therapies more accesible.

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Catalog Technologies https://indiebio.co/company/catalog-technologies/ Fri, 11 Apr 2025 22:09:14 +0000 http://localhost:10023/company/catalog-technologies/ “The Cloud” is basically just someone else’s computer, taking up acres of land and consuming cities’ worth of power, and billions of dollars in cost of ownership. It generates more carbon every year than the entire airline industry. The amount of data we produce each year as a species is growing exponentially, but our storage capacity is not. Hard drives not getting smaller–we’ve reached the physical limits of that. There are also serious concerns about the archival materials in the long term. Hard drives need to be replaced every 5 years, and magnetic tape can maybe last 30 years.

Catalog Technologies might be the solution to that. Their writer can write over a terabit of data onto DNA in a single day. The system is basically a printer, but instead of ink, it’s DNA. Not only can this store DNA, but it opens up new possiblities through which we interact with archival data: If you have millions of copies of your information (as DNA) you can operate on all of them in massively parallel ways.

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BioAesthetics https://indiebio.co/company/bioaesthetics/ Fri, 11 Apr 2025 22:09:12 +0000 http://localhost:10023/company/bioaesthetics/ BioAesthetics’ Nipple-Areolar Complex Graft, or NACgraft, is a revolutionary next step in breast reconstruction that will provide patients who have had mastectomies with a new, natural, living nipple and areola. The NACgraft is a cell-free, biologically-derived nipple and areola graft that once applied by a surgeon, will allow the patient’s own body to integrate the NACgraft. This process uses the patient’s own natural ability to heal, resulting in a real and living nipple unique to and uniquely a part of the patient.

They are currently engaged in a clinical stufy for their NAC, and beginning development of enhanced biologically derived grafts — capable of sustained drug delivery — to improve outcomes for third degree burn survivors through an NIH grant.

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AnimalBiome https://indiebio.co/company/animalbiome/ Fri, 11 Apr 2025 22:09:11 +0000 http://localhost:10023/company/animalbiome/ AnimalBiome creates microbiome-based therapeutics to treat the more than 9 million cats and dogs in the US living with chronic digestive disorders. They have developed a patent pending process for creating a fecal microbiota transplant pill that is stable at room temperature and highly effective. Animal Microbiome has been treating cats and dogs for more than 3 years and over 90% have shown a decrease in the frequency of diarrhea, vomiting, and/or constipation. In the course of creating this product, they have also created the world’s largest database of microbiome samples in the order Carnivora, and are leverage this database to create next generation probiotics and veterinary diagnostics.

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STÄMM https://indiebio.co/company/stamm/ Fri, 11 Apr 2025 22:09:09 +0000 http://localhost:10023/company/stamm/ Biology is the best platform for manufacturing cells. It can grow and produce all kinds of biomaterials very effectively. But for humans to be able to tap into this potential, we have to build bioreactors and figure out how to scale them in order to produce the massive amounts of biomaterials we need.

Bioreactors technology is very different when you’re optimizing for one reaction at one liter versus 100,000 liters, but this is where Stämm comes in. They are reinventing the way bioreactors work by developing a modular microfluidic platform that controls all the physical parameters, such as nutrients and dissolved oxygen, in a controlled environment. Unlike traditional bioreactor systems, their microfluidic bioreactor scales by adding more modules to increase the size of the reactor.

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Sun Genomics https://indiebio.co/company/sun-genomics/ Fri, 11 Apr 2025 22:09:09 +0000 http://localhost:10023/company/sun-genomics/ It all begins in the gut. We know that a balanced gut microbiome is key to a healthy (and happy) life. Probiotics, ingestible products that contain healthy bacteria and yeast, are available for people to buy and help with their digestive issues. But not all probiotics are created equal.

Sun Genomics found that an individual’s genome can help identify which probiotic strains are best for the person. By creating personalized probiotics, the company can eliminate the guesswork that’s involved with buying probiotics off the shelf and help people regain control of their health. Customers of all ages (babies, tots, adults) can get a whole genome sequencing of their gut microflora now, and get custom-tailored probiotics sent to their door right away, with the Floré product by Sun Genomics.

Sun Genomics has also launched a new academic collaboration focused on understanding the potential link between the gut microbiome and the Autism Spectrum Disorder

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Prime Roots https://indiebio.co/company/prime-roots/ Fri, 11 Apr 2025 22:09:06 +0000 http://localhost:10023/company/prime-roots/ Killing an animal and eating its flesh is not the only way to gain protein. Now more than ever, we need alternatives to conventional animal farming and fishing—not just because of animal welfare, but for human and environmental health. What’s happening now is not sustainable.

Prime Roots uses fungi as a complete protein source which acts as a seafood alternative. Described as healthful, protein-rich, sustainable, ethical, and delicious, the company is working to help people reimagine meat and seafood with fungi, that has the proper taste, texture, and nutrition. The product has already been tested with over 10,000 potential consumers, and their full product line is hitting markets and available for purchase on their website.

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NovoNutrients https://indiebio.co/company/novonutrients/ Fri, 11 Apr 2025 22:09:03 +0000 http://localhost:10023/company/novonutrients/ As the world’s population continues to balloon, demand for seafood is going with it. Aquaculture is the primary method to meet demand, but relies on feeding billions of small fish to larger fish. A process that is inherently unsustainable and is only getting worse as ocean fish supply dwindles. C.E.O. David Tze started his journey investing in an aquaculture investment management company, when he saw the need for a growing food and protein supply.

NovoNutrients is looking to solve this problem with a radically different approach, growing high-quality bacterial protein from waste carbon dioxide. Their microbes break down industrial emissions of carbon dioxide and reassemble them into low-cost and nutrient-rich aquaculture feed and specialty ingredients, which sequesters the pollution and turns it into high-value proteins.

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Michroma https://indiebio.co/company/michroma/ Fri, 11 Apr 2025 22:09:01 +0000 http://localhost:10023/company/michroma/ The vast majority of food dyes used today are synthetic chemicals derived from petroleum which have been linked to allergies, hyperactivity, and even cancer. Biocolorants do exist, but they are expensive to use and don’t hold their color when cooked or processed; insect-based dyes aren’t halal, vegan or kosher.

Michroma’s sustainable solution uses edible fungi cells that express the natural colorant into the bioreactor. No solvents are needed to extract and purify the color. The performance characteristics of their dyes are far superior to existing biocolorants.

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Intrinsic Medicine (fka Lupa Bio) https://indiebio.co/company/intrinsic-medicine-fka-lupa-bio/ Fri, 11 Apr 2025 22:08:57 +0000 http://localhost:10023/company/intrinsic-medicine-fka-lupa-bio/ Modern diseases are a result of cultural evoluton outpacing biology, and so inflammation has become maladaptive. The safety issues limit thet current repertoire of anti-inflammatory drugs from serving a majority of patients. In 2018, human milk oligosaccharides (HMOs) were discovered in the blood of pregnant women and an epidemiological study showed that elevated levels of key HMOs were associated with rheumatoid arthritis remission. Out of the 600 quintillion potential glycans, 300 million years of mammalian evolution have sorted out 200+ HMOs that are functionally bioactive in the body.

Intrinsic Medicine is a platform company innovative safe, bioactive sugars (like those HMOs) as a new therapeutic modality. With a combined 30 years of pharmaceutical industry experience at Ionis, Jason and Alex have been are using two key HMOs to be the only safe and effective solution for young people with irritable bowel syndrome, and they are taking their lead assets to clinical trial now.

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