United States – IndieBio – #1 in Early Stage Biotech https://indiebio.co #1 in Early Stage Biotech Tue, 29 Apr 2025 11:38:23 +0000 en-US hourly 1 https://wordpress.org/?v=6.7.2 https://indiebio.co/wp-content/uploads/2025/04/cropped-cropped-indie-bio-logo-512-32x32.png United States – IndieBio – #1 in Early Stage Biotech https://indiebio.co 32 32 NotCo https://indiebio.co/company/notco/ Fri, 11 Apr 2025 22:09:20 +0000 http://localhost:10023/company/notco/ For decades, food R&D has been dedicated to make foods that are tasty, cheap, and profitable. In Matias Muchnik’s words, “that’s why the pinnacle of food R&D is a freaking Dorito.” That’s why the team at NotCo wanted to steer the next wave of food R&D to make it healthy, delicious, and affordable, focusing largely on plant-based foods. Why? First, it’s healthier and more sustainable. Second, Millennials’ preferences are driving this market and have already carved out $15 billion of growth.

NotCo is on a mission to take animals out of food production while not compromising on taste and nutrition. Their animal-free dairy and meat products are powered by Giuseppe – an AI platform with embedded food science to generate healthy and accessible products from plants. The company analyzes at a molecular level to indicate which plants must be combined in order to replicate their taste, texture, color and aroma, enabling manufacturers to discover a new source of fiber, calcium and proteins from the vegetables. NotCo delivers unprecedented experiences in milk, mayo, ice cream, plant-based meats; all tasting like the real thing.

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MycoWorks https://indiebio.co/company/mycoworks/ Fri, 11 Apr 2025 22:09:18 +0000 http://localhost:10023/company/mycoworks/ MycoWorks is a biotechnology company founded by artists with the mission to create a platform for the highest quality materials using Fine Mycelium . Drawing on over two decades of pioneering research and innovation by our creative founding team, MycoWorks’ proprietary Fine Mycelium platform has enabled a new class of premium, non-animal materials that are the next evolution in mycelium. The company mission is to using the tools of biotechnology, manufacturing excellence and creative, master craftsmanship to grow the future of materials.

MycoWorks is at the forefront of the movement to bring circularity and sustainability to the fashion industry. They recently annouced a landmark partnership with Hermès for a new material Sylvania, a hybrid of nature and biotechnology. Fine Mycelium™, the genesis of Sylvania, is produced in the MycoWorks facility. It is then tanned and finished in France by the Hermès tanners to further refine its strength and durability, and shaped into a luxury travel bag at the workshops by the Hermès craftspeople. The company’s flagship product Reishi™ — a non-animal, non-plastic leather that performs like cowhide — designed as a proprietary woven cellular microstructure inspired from animal leather. Reishi™ is available for sale for stakeholders across the textiles industry from running shoes to the runway.

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mFluiDX https://indiebio.co/company/mfluidx/ Fri, 11 Apr 2025 22:09:18 +0000 http://localhost:10023/company/mfluidx/ Three years before COVID made everyone care about rapid molecular diagnostics, mFluiDx was already working on it. They were fighting epidemics before it was cool. Their initial prototype, funded by The Gates Foundation and DARPA, was working on rapid diagnostics for Zika virus. When patients would normally have to wait for days to get a result. mFluiDx’s prototype offered them an accurate diagnosis faster than a Spanish siesta, and 100X cheaper than a PCR setup.

mFluiDx presents a fast and portal DNA-based technology for identifyuing outbreaks of dangerous diseases in the field. Using microfluidics, they’ve engineered a field-ready, affordable, sensitive, and rapid approach that democratizes high-need diagnostics for everyone in the world.

mFluiDx selected as one of the top 20 startups to pitch at TechCrunch Startup Battlefield, from a pool of 900 startups globally.

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Girihlet https://indiebio.co/company/girihlet/ Fri, 11 Apr 2025 22:09:16 +0000 http://localhost:10023/company/girihlet/ The complexity and growing prevalence of autoimmune disorders demands attention. Baked into our immune cells are records of the interplay between the genome, diet, and the environment.

Girihlet’s patented approach to sequencing T-cell receptors (TCR) unlocks these complex interactions by classifying TCRs into actionable biomarkers to diagnose and identify treatment avenues for autoimmune diseases.

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Finless Foods https://indiebio.co/company/finless-foods/ Fri, 11 Apr 2025 22:09:16 +0000 http://localhost:10023/company/finless-foods/ Finless Foods is committed to creating a future where the ocean thrives. Co-founders Michael Selden and Brian Wyrwas founded the company to create delicious, healthy, and accessible plant-based and cell-cultured seafood alternatives.

Finless Foods offers options for all palates and dietary preferences, providing consumers with a range of responsibly produced food products to diversify their daily habits and pave the way toward a more sustainable future and healthier ocean.

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Indee Labs https://indiebio.co/company/indee-labs/ Fri, 11 Apr 2025 22:09:16 +0000 http://localhost:10023/company/indee-labs/ With their microvortex shedding technology, Indee Labs’ cell engineering platform preserves cell function while boasting high recovery efficiencies and each 5 x 10mm chip can process >50 million cells at >2-4 million cells per second and as low as 100uL in processing volume.

This matters to the population of patients who today cannot afford cell therapy due to the high cost associated with their production. With this system, the ability to engineer T-cells rapidly and more efficiently will make cell therapies more accesible.

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Endless West https://indiebio.co/company/endless-west/ Fri, 11 Apr 2025 22:09:15 +0000 http://localhost:10023/company/endless-west/ After a whiskey is fermented and distilled, it has to undergo an aging process, which is arguably the most expensive part of the process. The alcohol sits in contact with specially chosen wooden barrels whose wood contain compounds that are transferred to the whiskey, giving it exquisite flavor along with its color. Now imagine the same unique flavor profiles but for every spirit: wine, soju, sake, etc.

Endless West can simulate this process by analyzing the molecules that give spirits their flavors and aroma, and then synthesize their own “molecular” spirits, without the need for grapes, rice, or wood. Their first product, Glyph, is the first whiskey ever to be crafted ‘note by note’, using molecules (or, flavor and aroma notes) extracted in their purest form from more efficient sources in nature.

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Dahlia Biosciences https://indiebio.co/company/dahlia-biosciences/ Fri, 11 Apr 2025 22:09:15 +0000 http://localhost:10023/company/dahlia-biosciences/ Dahlia Biosciences is leading the development of cell-based RNA detection tools using CRISPR technology. The foundational RNA-targeting Cas9 technology was invented by Dr. Mitchell O’Connell and Dr. Sam Sternberg in the laboratory of Dr. Jennifer Doudna at UC Berkeley.

The company is dedicated to empower scientists to study and isolate cells at high resolution via sensitive, robust, and multiplexed RNA detection in both fixed and live cells. Their CRISPR based RNA detection reagents will plug seamlessly into existing flow cytometry workflows, reducing the time and cost-basis of research and development. Their kits and reagents can supercharge the many applicaitons based on fixed-cell analysis and live-cell sorting with wide-ranging implications for detection of disease to design of biomarkers and drugs.

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Catalog Technologies https://indiebio.co/company/catalog-technologies/ Fri, 11 Apr 2025 22:09:14 +0000 http://localhost:10023/company/catalog-technologies/ “The Cloud” is basically just someone else’s computer, taking up acres of land and consuming cities’ worth of power, and billions of dollars in cost of ownership. It generates more carbon every year than the entire airline industry. The amount of data we produce each year as a species is growing exponentially, but our storage capacity is not. Hard drives not getting smaller–we’ve reached the physical limits of that. There are also serious concerns about the archival materials in the long term. Hard drives need to be replaced every 5 years, and magnetic tape can maybe last 30 years.

Catalog Technologies might be the solution to that. Their writer can write over a terabit of data onto DNA in a single day. The system is basically a printer, but instead of ink, it’s DNA. Not only can this store DNA, but it opens up new possiblities through which we interact with archival data: If you have millions of copies of your information (as DNA) you can operate on all of them in massively parallel ways.

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Circularis https://indiebio.co/company/circularis/ Fri, 11 Apr 2025 22:09:14 +0000 http://localhost:10023/company/circularis/ Circularis’s technology screens a huge library of promoters in a single cell. Through directed evolution selection, the strongest promoters rise to the top and can be identified and incorporated into a host of gene expression applications, such as biomanufacturing and gene therapy. Beyond just promoters, their technology also works for enhancers, silencers/repressers, stability sequences, and nuclear delivery sequences. The process happens within days, instead of months.

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