Israel – IndieBio – #1 in Early Stage Biotech https://indiebio.co #1 in Early Stage Biotech Tue, 29 Apr 2025 14:32:42 +0000 en-US hourly 1 https://wordpress.org/?v=6.7.2 https://indiebio.co/wp-content/uploads/2025/04/cropped-cropped-indie-bio-logo-512-32x32.png Israel – IndieBio – #1 in Early Stage Biotech https://indiebio.co 32 32 Diptera.ai https://indiebio.co/company/dipteraai/ Fri, 11 Apr 2025 22:08:08 +0000 http://localhost:10023/company/dipteraai/ Mosquito-borne diseases like dengue, Zika and malaria infect hundreds of millions every year. Global warming is driving these mosquitoes to spread rapidly, endangering many more.

Diptera.ai’s technology cuts the cost of sterile insect control (SIT) – a natural and highly efficient insect birth control method – to make it a widespread solution against mosquitoes. Diptera.ai combines computer vision and deep biological knowledge to fight mosquitoes and their diseases. Diptera.ai uses non-GMO technology that eliminates the need to build a mosquito rearing and sorting facility near every release site.

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Ceal https://indiebio.co/company/ceal/ Mon, 17 Mar 2025 17:46:32 +0000 https://indiebio.co/company/ceal/ Ceal, a carbon dioxide removal (CDR) company, is paving the way for a Net-Zero environment using the most energy-efficient technology ready to scale.
Using its proprietary technology, Ceal’s innovative process utilizes the existing infrastructure of industrial facilities to provide the cheapest gigaton-scale CDR operation. The process is additive- and emission-free, and non-reliant upon the carbon market.
In a highly efficient single-step, Ceal captures and sequesters atmospheric CO2 dissolved in seawater into industry-essential minerals, while providing soft water for various uses. Thus, enabling major cost savings and substantial new revenues for its customers. Ceal’s solution reduces the carbon footprint of the industrial facility, its marine pollution of hazardous chemicals, and simplifies its operation.
Ceal – more than just carbon dioxide removal. We heal the world.

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DisperseBio https://indiebio.co/company/dispersebio/ Mon, 17 Mar 2025 16:40:50 +0000 https://indiebio.co/company/disperse-bio/ Peptide-based solution that disrupts the growth of biofilms by activating the microbe’s natural self biofilm dispersion pathway

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Starstone https://indiebio.co/company/starstone/ Tue, 25 Feb 2025 20:29:59 +0000 http://localhost:10023/company/starstone/ Global demand for cement, a key ingredient in concrete, is expected to grow from 4.2 billion tons today to 6.2 billion by 2050. The construction industry relies on it to build everything from homes and buildings to roads and bridges to dams and seawalls. Cement, however, is responsible for almost 90% of concrete emissions. So far, technologies that eliminate cement (or clinker, cement’s carbon-intensive bonding agent) have failed because they cannot scale or compete on cost.

Starstone is developing a bio-concrete that removes cement from the equation. Instead of hauling rock from quarries to kilns to make cement, Starstone grows bacterial cement in fermentation tanks situated at concrete casting facilities. Once that bio-cement is combined with the usual sand aggregate and water, it functions like conventional concrete and slashes the emissions per ton by at least 70%.

Starstone’s proprietary technologies include genetically modified bacteria mixes, enzymatic active ingredients, upcycled bacteria feed, recyclable media, and aggregates sourced from industrial byproducts. These will make Starstone concrete cost-competitive with conventional concrete at scale.

Starstone co-founders, Gabriel Peer and Reut Sorek Abramovich, PhD, and their teammates bring experience in construction, fermentation, microbiological structures, and biomineralization. At IndieBio Demo Day, the Tel Aviv-based company will have a hybrid, bio-concrete breeze block – type of decorative concrete block – made with 50% less cement than conventional concrete. It will illustrate Starstone’s potential to eliminate carbon-intensive steps from concrete production without compromising on cost or quality.

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Climate Crop https://indiebio.co/company/climate-crop/ Tue, 25 Feb 2025 20:29:51 +0000 http://localhost:10023/company/climate-crop/ Photosynthesis wastes sunlight. Many scientific efforts are underway to reengineer photosynthesis to increase yields. Climate Crop – 5 years in the making at Weizmann Institute – will outgrow them all.

It works in all vascular plants. It’s simple – downregulating one enzyme. During the day, plants increase their storage of transient starch; at night, they use this starch as building blocks for all cell matter. Climate Crop simply increases the storage of transient starch – then the plant takes it from there.

Climate Crop will power applications across agriculture and industrial markets. Higher yielding cotton. More affordable animal feed. Carbon-sucking poplars. Aviation fuels from rapeseed.

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Carbonade https://indiebio.co/company/carbonade/ Tue, 25 Feb 2025 20:29:50 +0000 http://localhost:10023/company/carbonade/ Carbon capture, utilization and storage has a dirty little secret that divides its proponents and opponents: capturing CO2 out of the air is cheap, but then releasing it from its capture solvent into a purified tank is up to 10x more energetically and financially costly. This is one of the reasons why opponents argue we’ll never remove enough carbon cheaply enough to be economically viable.

Carbonade can put this argument to rest, because they’ve figured out how to skip the expensive “releasing” step, and go straight to utilization. How? Because their electrochemical cell operates at the lowest ever recorded energy required for “cracking the CO2 molecule.” The technology comes out of Professor Ronny Neumann’s lab at the Weizmann Institute, where they’ve developed a proprietary electrocatalyst that transforms the CO2 while it’s still in the capture solvent. So in one step, Carbonade captures the CO2 from ambient air into its solvent, and immediately converts it to a usable carbon substrate (e.g., carbon monoxide), while also producing green hydrogen, all without having to purify the CO2 and ship it to another “utilization” provider. This is all to make products like sustainable aviation fuels (SAFs) for jets, a topic the CEO knows a thing or two about, as a retired F-16 pilot.

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Asterix Foods https://indiebio.co/company/asterix-foods/ Tue, 25 Feb 2025 20:29:11 +0000 http://localhost:10023/company/asterix-foods/ Industry leading companies like Impossible, Perfect Day (RebelBio), and EVERY (IndieBio) have shown the powerful commercial appeal of animal-free proteins. Behind this first wave comes a second wave: glycoproteins.

Glycoproteins require precise glycosylations to accurately fold, recognize, and bind – driving functional performance needed in the food industry. To unlock this second wave of animal-free proteins, Asterix Foods is using plant cell culture, because plant cells can easily achieve glycosylations that microbial fermentation is challenged by.

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Nitrofix https://indiebio.co/company/nitrofix/ Tue, 25 Feb 2025 20:29:08 +0000 http://localhost:10023/company/nitrofix/ In order to supply our agriculture and industries with an available source of nitrogen, we rely on a chemical process that requires 400˚C of heat and more pressure than at the bottom of the world’s deepest lake. It’s no wonder that ammonia production releases 500 million tons of CO2 annually (3% of the world’s carbon emissions). Producing green ammonia is a tall order that has puzzled chemists for decades.

With inspiration from nature, Nitrofix has designed a readily-available catalyst that can produce ammonia at room temperature and pressure, thereby nearly eliminating the heat and pressure (and thus carbon) costs. This might sound too good to be true, but their electrochemical process can produce ammonia using the voltage of a standard AA battery. Using the innovation from a renowned Weizmann Institute lab, they’ve already produced ammonia at the benchtop in the first weeks of IndieBio, and they are currently finishing an industrially scalable prototype in time for Demo Day.

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Ingrediome https://indiebio.co/company/ingrediome/ Tue, 25 Feb 2025 20:29:01 +0000 http://localhost:10023/company/ingrediome/ At Ingrediome, we create real meat and seafood by using photosynthetic precision fermentation to create nature-identical animal proteins. These key functional proteins capture a great deal of the taste, looks and texture of meat while enabling us to make clean-label products with better nutritional values even compared with traditional meat.

During the past 2 years, we’ve gone from lab setup to cultivating cyanobacteria in a 100 Liter Photobioreactor and now working on tripling this scale this year, with minimal costs for such scale, 100X cheaper than the equivalent steel tank system

Our first deli meat products attracted the attention of Israel’s major deli meat producer, a leading European ingredient manufacturer with which we will commence R&D collaborations. Our first seafood products earned us a spot as one of the 3 finalists of the Thai-Union innovation challenge.

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